MIT Technologies Assessment, as a rule, focuses on the technological know-how first—the breakthrough, the shock, the accidental discovery with the likely to upend the way we are living. Our once-a-year look at 35 superb innovators under 35 is a reminder that driving all those people innovations are people today with desires, fears, and ambitions. Often they hack away at a problem for years just before figuring out a way forward. Often they stumble on a option they did not know they ended up browsing for. We hope these portraits offer a sense of the selection of work getting completed in technological know-how, and a sense of what’s coming next.